The Cavaliers are handing the Pacers a third loss in a row after taking down Indiana 127-124 on the road.
Darius Garland led all scorers with 41 points and dished out a game-high 13 assists in the victory.
Evan Mobley also had a double-double with 22 points and 12 rebounds. Tyrese Haliburton led the Pacers in scoring with 25 points.
Malcolm Brogdon collected 12 points and 12 assists in the loss. Indiana is now 22-and-45 while the Cavaliers improved to 38-and-27.