Xander Bogaerts cracked two solo homers to help the Red Sox cruise to a 10-4 win over the Indians at Fenway Park.
Edwin Encarnacion connected for a pair of two-run blasts in the loss.
Carlos Carrasco didn't make it out of the fourth inning, giving up five earned runs on eight hits to fall to 15-and-7.
The Indians and Red Sox close out their four-game series at Fenway Park this afternoon.
Cleveland is 73-and-53, 13 games ahead of the Twins for first in the AL Central.
Adam Plutko starts for the Indians opposite Boston's David Price.