Adalberto Mondesi homered, swiped two bases and scored both runs to lead the Royals to a 2-1, 10-inning victory over the Indians in Kansas City.
Jose Ramirez's first-inning sac-fly scored Cleveland's lone run. Neil Ramirez was the losing pitcher.
There's three games left in the regular season for the Indians.
Cleveland and the Royals play tonight at "The K."
The AL Central champions have their eyes set on an ALDS matchup with the Astros beginning next week.
Mike Clevinger starts for the Indians opposite Kansas City's Ian Kennedy.